Jo Van Ginderachter is Lab Director of the Myeloid Cell Immunology lab at VIB
(Center for Inflammation Research) and of the Cellular and Molecular Immunology lab at
Vrije Universiteit Brussel. He has a long-standing expertise in macrophage biology, tumour
immunology and applications of nanobodies. He published over 100 peer-reviewed articles and 4 book chapters on these topics. Most of the grants of the Van Ginderachter lab are dealing with the characterization of tumour-associated macrophages and dendritic cells, several of which deal with nanobody-mediated imaging or therapy.
Mucosal Immunol. 2022 Sep 7. doi: 10.1038/s41385-022-00563-2. Online ahead of print.
Monocyte-derived macrophages (Mφs) are crucial regulators during muscularis inflammation. However, it is unclear which micro-environmental factors are responsible for monocyte...
Nat Protoc. 2022 Oct;17(10):2354-2388. doi: 10.1038/s41596-022-00716-4. Epub 2022 Aug 5.
Brain-immune cross-talk and neuroinflammation critically shape brain physiology in health and disease. A detailed understanding of the brain immune landscape is essential for...
Adv Drug Deliv Rev. 2022 May;184:114239. doi: 10.1016/j.addr.2022.114239. Epub 2022 Mar 26.
The important role of tumor microenvironmental elements in determining tumor progression and metastasis has been firmly established. In particular, the presence and activity...
Cell Rep. 2021 Dec 28;37(13):110171. doi: 10.1016/j.celrep.2021.110171.
Macrophages are often prominently present in the tumor microenvironment, where distinct macrophage populations can differentially affect tumor progression. Although metabolism influences macrophage...
Front Immunol. 2021 Nov 30;12:777524. doi: 10.3389/fimmu.2021.777524. eCollection 2021.
Glioblastoma (GBM) is the most common malignant primary brain tumor. Glioblastomas contain a large non-cancerous stromal compartment including various populations of tumor-associated...